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Bavarian Nordic A/S obtains US$120m funding to advance smallpox vaccine development

Bavarian Nordic A/S, a Danish biotechnology company, has recently secured a significant funding of US$120 million to further advance its smallpox vaccine development. This funding will play a crucial role in accelerating the company’s efforts to combat this deadly disease and protect global populations.

Smallpox, caused by the variola virus, was one of the most devastating diseases in human history. It claimed the lives of millions of people before being declared eradicated in 1980, thanks to a successful global vaccination campaign led by the World Health Organization (WHO). However, concerns about the potential re-emergence of smallpox as a bioweapon or through natural sources have prompted the need for continued research and development of effective vaccines.

Bavarian Nordic has been at the forefront of smallpox vaccine development for over two decades. The company’s leading candidate, known as IMVAMUNE®, is a non-replicating smallpox vaccine that has shown promising results in clinical trials. Unlike traditional vaccines, IMVAMUNE® does not contain live virus particles, making it safe for individuals with weakened immune systems or other contraindications.

The recent funding injection will enable Bavarian Nordic to conduct large-scale clinical trials and expand its manufacturing capabilities. The company aims to increase its production capacity to meet potential global demand in case of a smallpox outbreak. Additionally, the funding will support further research into improving the vaccine’s efficacy and exploring its potential applications in other viral diseases.

One of the key advantages of IMVAMUNE® is its ability to be stockpiled for long periods without losing potency. This feature makes it an ideal candidate for emergency preparedness and response efforts. In fact, the U.S. government has already stockpiled a significant quantity of IMVAMUNE® as part of its strategic national stockpile program.

The funding was secured through a combination of sources, including a private placement of shares and a loan from the European Investment Bank (EIB). This demonstrates the confidence and support from both private investors and public institutions in Bavarian Nordic’s smallpox vaccine development program.

The company’s success in obtaining this funding is a testament to its strong track record in vaccine development and its commitment to addressing global health challenges. Bavarian Nordic has previously developed and commercialized vaccines for other infectious diseases, such as Ebola and RSV (respiratory syncytial virus). This expertise and experience have positioned the company as a trusted partner in the fight against infectious diseases.

With the additional funding, Bavarian Nordic aims to expedite the regulatory approval process for IMVAMUNE® in various countries, including the United States. The company is also exploring potential collaborations with other organizations to further enhance the vaccine’s effectiveness and broaden its applications.

In conclusion, Bavarian Nordic’s recent US$120 million funding will significantly advance the development of its smallpox vaccine, IMVAMUNE®. This funding will support large-scale clinical trials, expand manufacturing capabilities, and further research into improving the vaccine’s efficacy. With its unique characteristics and potential applications in emergency preparedness, IMVAMUNE® holds great promise in protecting global populations against the re-emergence of smallpox.

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