{"id":2546565,"date":"2023-06-14T11:07:08","date_gmt":"2023-06-14T15:07:08","guid":{"rendered":"https:\/\/platoai.gbaglobal.org\/platowire\/scientists-from-cornell-university-reveal-key-mechanism-responsible-for-immune-evasion-in-lung-cancer\/"},"modified":"2023-06-14T11:07:08","modified_gmt":"2023-06-14T15:07:08","slug":"scientists-from-cornell-university-reveal-key-mechanism-responsible-for-immune-evasion-in-lung-cancer","status":"publish","type":"platowire","link":"https:\/\/platoai.gbaglobal.org\/platowire\/scientists-from-cornell-university-reveal-key-mechanism-responsible-for-immune-evasion-in-lung-cancer\/","title":{"rendered":"Scientists from Cornell University Reveal Key Mechanism Responsible for Immune Evasion in Lung Cancer"},"content":{"rendered":"

\"\"<\/p>\n

Lung cancer is one of the most common types of cancer worldwide, and it is also one of the deadliest. Despite advances in treatment options, the five-year survival rate for lung cancer patients remains low. One of the reasons for this is that lung cancer cells have the ability to evade the immune system, making it difficult for the body to fight off the cancer.<\/p>\n

However, a recent study by scientists from Cornell University has shed light on a key mechanism responsible for immune evasion in lung cancer. The study, which was published in the journal Nature Communications, identified a protein called B7-H3 that is overexpressed in lung cancer cells and plays a critical role in suppressing the immune response.<\/p>\n

The researchers found that B7-H3 interacts with a receptor on immune cells called T cells, which are responsible for recognizing and attacking cancer cells. When B7-H3 binds to this receptor, it sends a signal to the T cell to shut down its activity, effectively disabling the immune response.<\/p>\n

This discovery is significant because it provides a potential target for new therapies that could help overcome immune evasion in lung cancer. By blocking the interaction between B7-H3 and T cells, it may be possible to restore the immune response and improve outcomes for lung cancer patients.<\/p>\n

The study also highlights the importance of understanding the complex interactions between cancer cells and the immune system. While immunotherapy has shown promise in treating some types of cancer, it is not effective for all patients. By identifying specific mechanisms of immune evasion, researchers can develop more targeted therapies that are tailored to individual patients and their unique cancer biology.<\/p>\n

Overall, the findings of this study represent an important step forward in our understanding of lung cancer and its interactions with the immune system. While there is still much work to be done, this research provides hope for new treatments that could improve outcomes for lung cancer patients and ultimately lead to a cure.<\/p>\n